AMES (mutagenicity)

AMES bacterial mutagenicity benchmark — standard gentox endpoint.

Composite

79.5

Experimental validation

Retrospective

Stages

IND-enablingLead ID / ADMET

Modalities

small-molecule

Task types

toxicity-classification

Size

molecules: 7,278

License

MIT

First release

2021-02

Last updated

2025-01

Official site

→ project page

Leaderboard

→ leaderboard

Dataset

→ dataset

Code / GitHub

→ repository

HuggingFace

→ HF

Paper

Therapeutics Data Commons · Huang K, Fu T, et al. · 2021 · paper · doi:10.48550/arXiv.2102.09548 · 620 citations

Flags

none

Experts

Kexin Huang

Groups

Therapeutics Data Commons

Hosted by

Therapeutics Data Commons (TDC), Drug Discovery Benchmarks (DDB)

Related benchmarks

TDC ADMET Group, Tox21

Rubric (7-criterion)

rigor

coverage

maintenance

adoption

quality

accessibility

industry_relevance

Notes

Core gentox endpoint.

← Back to all benchmarks

Compare:

Open comparison →