Open Systems Pharmacology / PK-Sim
OSP Suite — open PBPK/QSP models and validation sets.
Composite
80.3
Experimental validation
Retrospective
Stages
Phase IIND-enabling
Modalities
small-moleculebiologic-mab
Task types
pbpk-validation
Size
models: 100
validated_compounds: 50
validated_compounds: 50
License
GPL-2.0
First release
2017
Last updated
2025-01
Official site
Leaderboard
→ leaderboard
Dataset
Code / GitHub
HuggingFace
→ HF
Paper
The Open Systems Pharmacology Suite: a new era in PBPK modeling · Lippert J, Burghaus R, Edginton A, et al. · 2019 · paper · doi:10.1002/psp4.12386 · 180 citations
Flags
none
Experts
—
Groups
Hosted by
—
Related benchmarks
Rubric (7-criterion)
rigor
5
coverage
3
maintenance
4
adoption
3
quality
4
accessibility
5
industry_relevance
4
Notes
Open alternative to Simcyp.