PubChem BioAssay

NIH PubChem's screening assay repository.

Composite
88.6
Experimental validation
Wet-lab confirmed
Stages
Hit ID
Modalities
small-molecule
Task types
bioactivity
Size
assays: 1,700,000
compounds: 114,000,000
License
Public domain
First release
2004
Last updated
2025-05
Official site
→ project page
Leaderboard
→ leaderboard
Dataset
→ dataset
Code / GitHub
→ repository
HuggingFace
→ HF
Paper
PubChem 2023 update · Kim S, Chen J, Cheng T, et al. · 2023 · paper · doi:10.1093/nar/gkac956 · 1,200 citations
Flags
none
Experts
Sunghwan Kim
Groups
NIH NCBI (PubChem)
Hosted by
Related benchmarks
ChEMBL, MoleculeNet

Rubric (7-criterion)

rigor
4
coverage
5
maintenance
5
adoption
5
quality
3
accessibility
5
industry_relevance
4

Notes

Broadest HTS repository; quality heterogeneous.

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