Tox21
US Tox21 program HTS data on 12 nuclear receptor / stress response assays.
Composite
77.5
Experimental validation
Retrospective
Stages
Lead ID / ADMETIND-enabling
Modalities
small-molecule
Task types
toxicity-classification
Size
compounds: 10,000
assays: 12
assays: 12
License
Public
First release
2014
Last updated
2017
Official site
Leaderboard
→ leaderboard
Dataset
→ dataset
Code / GitHub
→ repository
HuggingFace
→ HF
Paper
Tox21 Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways · Huang R, Xia M, et al. · 2016 · paper · doi:10.3389/fenvs.2015.00085 · 1,100 citations
Flags
none
Experts
Groups
Hosted by
Related benchmarks
Rubric (7-criterion)
rigor
4
coverage
3
maintenance
2
adoption
5
quality
4
accessibility
5
industry_relevance
4
Notes
Field-standard tox benchmark; endpoint count small vs modern suites.