CASF-2016

Comparative Assessment of Scoring Functions — scoring, ranking, docking, screening power tests.

Composite
76.2
Experimental validation
Retrospective
Stages
Hit ID
Modalities
small-moleculeprotein-general
Task types
scoring-function-eval
Size
complexes: 285
decoy_poses: 28,500
License
Academic-only
First release
2016
Last updated
2019
Official site
→ project page
Leaderboard
→ leaderboard
Dataset
→ dataset
Code / GitHub
→ repository
HuggingFace
→ HF
Paper
Comparative Assessment of Scoring Functions: The CASF-2016 Update · Su M, Yang Q, Du Y, et al. · 2019 · paper · doi:10.1021/acs.jcim.8b00545 · 430 citations
Flags
none
Experts
Renxiao Wang
Groups
SIMM, Chinese Academy of Sciences
Hosted by
PDBbind / CASF
Related benchmarks
PDBbind, PoseBusters, PLINDER

Rubric (7-criterion)

rigor
5
coverage
3
maintenance
2
adoption
5
quality
4
accessibility
3
industry_relevance
4

Notes

Authoritative scoring-power eval; update cadence slow.

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